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Research highlight: an early trial of an mRNA vaccine in EBV-linked tumours

Vaccine vials and a syringe on a chilled laboratory tray.

AI-assisted summary Written by WellCareChina with AI assistance and checked against the original article.

A research highlight in Cancer Communications on 21 August 2026 summarises an early-stage trial (NCT05714748) of WGc-043, an mRNA vaccine developed by WestGene Biopharma, in patients with Epstein-Barr virus (EBV)-positive nasopharyngeal carcinoma and natural killer/T-cell lymphoma. The highlight reports disease control rates of 66.67% and 57.14% respectively and a favourable tolerability profile, and notes that EBV infects more than 90% of people worldwide and is linked to several cancers. The piece presents the findings as early clinical evidence pointing to a research direction, not as an approved treatment.

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Source tier A — open-access research highlight (CC BY 4.0); the link goes to the PubMed record because the publisher site blocks automated access (dev-083). Our own summary, no full-text copy.

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