肺癌Lung cancer

研究 A Phase II, Single-Arm, Prospective Study of Neoadjuvant Icotinib With Chemotherapy for the Treatment of Patients With Epidermal Growth Factor Receptor Mutation Positive, Resectable for Stage II to IIIB(N2) Non-small Cell Lung Cancer

主要研究者

Wu Nan · Principal Investigator

医院

Peking University Cancer Hospital

状态

招募中

登记库

NCT05104788

研究 A Phase I Study to Evaluate the Safety and Preliminary Efficacy of [225Ac]Ac-DOTATATE Injection Combined With Tislelizumab in the Maintenance Treatment Period for Patients of Extensive-stage Small Cell Lung Cancer (ES-SCLC) With Somatostatin Receptors (SSTR)+ as First-line Treatment

医院

Peking University Cancer Hospital

状态

招募中

登记库

NCT07413042

研究 Neoadjuvant Sintilimab or Combined With Chemotherapy for Stage III Driven Gene Mutation Negative Non-small Cell Lung Cancer

主要研究者

Peng Zhang · Director of thoracic department

医院

Shanghai Pulmonary Hospital

状态

招募中

登记库

NCT04728724

研究 Disitamab Vedotin in Combination with Tislelizumab and Bevacizumab in a Phase II Clinical Study of Locally Advanced or Metastatic Non-small Cell Lung Cancer with HER2 Mutation/amplification/expression

主要研究者

Chunxia Su · Director of the Clinical Research Center

医院

Shanghai Pulmonary Hospital

状态

招募中

登记库

NCT06749860

研究 Evaluation of AI-Assisted Versus Conventional Human Reading for Lung Cancer Screening in Community-Based Settings: A Randomized Controlled Trial

主要研究者

Jianxing He · Professor

医院

First Affiliated Hospital of Guangzhou Medical University

状态

招募中

登记库

NCT06988579

研究 Construction and Evaluation of a Hospital-Community Health Collaboration Model Empowered by Digital Technology for Lung Cancer Screening

主要研究者

Jianxing He · Director

医院

First Affiliated Hospital of Guangzhou Medical University

状态

招募中

登记库

NCT06988943

研究 Establishing a Longitudinal Cohort Study of Lung Cancer Using Tissue and Peripheral Blood Metabolomics to Explore Biomarkers and Therapeutic Mechanisms.

主要研究者

Jianxing He · Professor

医院

First Affiliated Hospital of Guangzhou Medical University

状态

招募中

登记库

NCT06843707

研究 Efficiency and Safety of Microwave Ablation Plus Immune Checkpoint Inhibitor for Patients With Multiple Primary Lung Cancer: A Open, Multi-center, Phase II Clinical Trial

主要研究者

Chang Chen

状态

招募中

登记库

NCT05053802

研究 A Phase 1/2 Study Evaluating the Safety and Efficacy of Amivantamab and Olomorasib Combination Therapy in Metastatic Non-small Cell Lung Cancer

医院

The First Affiliated Hospital, Sun Yat-sen University

状态

招募中

登记库

NCT07227025

研究 A Phase 3, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study to Evaluate the Anti-Tumor Efficacy and Safety of Sunvozertinib Versus Placebo as Adjuvant Therapy in Patients With Stage IB-IIIA Non-Small Cell Lung Cancer Harboring EGFR Exon 20 Insertion Mutations or PACC Mutations After Radical Surgery (WU-KONG16)

医院

Peking University Cancer Hospital

状态

招募中

登记库

NCT07182682

研究 Phase II Study of Neoadjuvant CT-Guided Intra-tumor Double Checkpoint Blockades for Untreated Stage I-IIIA Non-Small Cell Lung Cancers Amenable for Surgical Resection

医院

The Second Affiliated Hospital of Guangzhou Medical University

状态

招募中

登记库

NCT06492421

研究 A Phase III, Multicenter, Randomized, Controlled, Open-label Clinical Study to Evaluate the Efficacy and Safety of YL201 in Combination With Serplulimab Versus Carboplatin and Etoposide in Combination With Serplulimab as First-line Treatment in Participants With Treatment-naïve Extensive-stage Small Cell Lung Cancer

医院

Sun Yat-sen University Cancer Center

状态

招募中

登记库

NCT07739758

研究 Efficacy and Safety of Cryo-Thermal Ablation Combined With Toripalimab and Chemotherapy as Neoadjuvant Treatment for Resectable Stage IB-IIIB Non-Small Cell Lung Cancer: A Multicenter, Single-Arm, Prospective Phase II Clinical Trial

主要研究者

Hu Liao · Deputy Director & Medical Team Leader, Department of Thoracic Surgery, West China Hospital, Sichuan University; Associate Professor of Surgery; Master's Supervisor

医院

The Third People's Hospital of Chengdu

状态

招募中

登记库

NCT07855965

研究 A Phase 1/2 Adaptive Dose-Escalation and Expansion Study of Dual-Targeting Chimeric Antigen Receptor Natural Killer (CAR-NK) Cells Directed Against DLL3, CD56 (NCAM1), and/or GD2 in Adults With Relapsed/Refractory Small Cell Lung Cancer

医院

Peking University Shenzhen Hospital

状态

招募中

登记库

NCT07744256

研究 A Phase III, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Patients With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

医院

First Affiliated Hospital of Guangzhou Medical University

状态

招募中

登记库

NCT06793215

研究 A Prospective, Single Arm, Phase II Clinical Study of Tislelizumab Combined With Chemotherapy Followed by Thoracic Consolidation Radiotherapy in the First-line Treatment of Extensive Stage Small Cell Lung Cancer

主要研究者

Wei Zhou · Department Director

医院

Chongqing University Cancer Hospital

状态

招募中

登记库

NCT07425795

研究 Immunonutrition in Reducing Acute Esophagitis After Thoracic Radiotherapy in Lung Cancer: a Prospective, Randomized, Controlled, Open-label Clinical Trial

主要研究者

HuaiLiu · Prof.

医院

Hunan Cancer Hospital

状态

招募中

登记库

NCT06840704

研究 A Phase Ib/III Clinical Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Immunogenicity of HS-20117 Combined With Aumolertinib in Participants With Advanced Non-Squamous Non-Small Cell Lung Cancer

医院

Tianjin Medical University Cancer Institute & Hospital

状态

招募中

登记库

NCT06417008

研究 A Multicenter, Open-label, Dose-Escalation and Dose-Expansion Phase I/II Study of ZG005 Combined With Gecacitinib in Patients With Advanced Non-Small Cell Lung Cancer

医院

Shanghai Chest Hospital

状态

招募中

登记库

NCT06903377

研究 A Study of QL1706 Combined With Chemotherapy Induction on Sequential Immunotherapy Consolidation in Patients With Limited-Stage Small Cell Lung Cancer After Chemoradiotherapy：A Phase II Trial

主要研究者

Xuwei Cai · Director

医院

Shanghai Chest Hospital

状态

招募中

登记库

NCT07091305

研究 A Multicenter, Randomized, Controlled, Open-label, Phase IIa Trial on Autologous Tumor Infiltrating Lymphocyte Injection (LM103 TILs) for the Adjuvant Treatment of Non-small Cell Lung Cancer With Negative Driver Gene Mutations

医院

Guangdong Provincial People's Hospital

状态

招募中

登记库

NCT07444437

研究 Neoadjuvant Therapy With Toripalimab and JS004 Combined With Etoposide and Platinum Chemotherapy for Limited-stage Small Cell Lung Cancer : A Single-arm, Phase 2 Trial

主要研究者

Peng Zhang · Director

医院

Shanghai Pulmonary Hospital

状态

招募中

登记库

NCT06256237

研究 Exploration on the Value of Molecular Residual Disease Based on Circulating Tumor DNA Detection in Predicting Recurrence of Resected Non-small Cell Lung Cancer

主要研究者

Peng Zhang · Professor

医院

Shanghai Pulmonary Hospital

状态

招募中

登记库

NCT05965024

研究 Patient-derived Tumor-like Cell Cluster Model-based Precision Treatment Strategy on Non-small Cell Lung Cancer: a Prospective, Observational Study

主要研究者

Chang Chen · Deputy Director of MD. PhD. Program in Thoracic Surgery, Secretary of the party committee of Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China

医院

Shanghai Pulmonary Hospital

状态

招募中

登记库

NCT07328945

研究 Safety, Tolerability, Pharmacokinetics, Immunogenicity and Preliminary Efficacy Study of the Combination Therapy With HC010 for Injection in Patients With Advanced Solid Tumors:A Multicenter, Open-Label, Dose Range-Finding and Multiple Cohort Dose Expansion Phase Ib Clinical Trial-Lung Cancer Population

医院

Sun Yat-sen University Cancer Center

状态

招募中

登记库

NCT07381829

研究 A Prospective, Single-arm, Multicenter, Phase II Clinical Study on Envafolimab Combined With Disitamab Vedotin And Carboplatin for Resectable, Stage II-III, HER2-Mutant Non-Small Cell Lung Cancer

医院

Guangdong Provincial People's Hospital

状态

招募中

登记库

NCT06734182

研究 A Multicenter Phase II/III Study Evaluating the Efficacy and Safety of SCTB41 Combined With Chemotherapy Versus Tislelizumab Combined With Chemotherapy as First-Line Treatment for Driver-Negative Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

医院

Guangdong Provincial People's Hospital

状态

招募中

登记库

NCT07662395

研究 A Randomized, Open Label, Multicenter, Phase 3 Trial Evaluating the Efficacy and Safety of TAK-928 Versus Docetaxel in Participants With Unresectable Locally Advanced or Metastatic Non-Small Cell Lung Cancer With Disease Progression on or After Platinum-Based Chemotherapy and Anti-PD-1/PD-L1 Immunotherapy

医院

The First Affiliated Hospital of Anhui Medical University

状态

招募中

登记库

NCT07217301

研究 An Open-label, Multicenter Study of ZL-1310 to Evaluate the Safety, Efficacy, and Pharmacokinetics in Participants With Small Cell Lung Cancer

医院

The First Affiliated Hospital of Anhui Medical University

状态

招募中

登记库

NCT06179069

研究 Comparison of Segmentectomy Versus Lobectomy for Early-stage Non-small Cell Lung Cancer ≤ 2 cm in the Middle Third of the Lung Field: A Prospective and Multi-center RCT Study

医院

Jiangsu Province Hospital

状态

招募中

登记库

NCT04944563

研究 PADL1NK-005: A Randomized, Phase 3, Open-Label Study to Evaluate PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

医院

Anhui Provincial Hospital

状态

招募中

登记库

NCT07144280

研究 DAREON ® -Lung-1: A Phase III Multi-center, Open-label, Randomised Trial of Intravenous Obrixtamig in Combination With Atezolizumab, Carboplatin, and Etoposide vs. Atezolizumab, Carboplatin, and Etoposide as First-line Treatment in Patients With Extensive-stage Small Cell Lung Cancer

医院

Peking University Cancer Hospital

状态

招募中

登记库

NCT07472517

研究 A Global, Multicenter, Randomized, Open-label, Phase 3 Study of Sacituzumab Govitecan Versus Standard of Care (SOC) in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer (ES-SCLC)

医院

Peking University Cancer Hospital

状态

招募中

登记库

NCT06801834

研究 A Phase 3, Multicenter, Randomized, Open-label Study Evaluating Efficacy of Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Subjects With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers, Negative for PD-L1, and Positive for KRAS p.G12C (CodeBreaK 202)

医院

First Affiliated Hospital of Guangzhou Medical University

状态

招募中

登记库

NCT05920356

研究 Tranexamic Acid Use for Bleeding Prevention in the Surgical Treatment of Metastatic Spinal Tumor in Lung Cancer Patients: a Triple Blinded, Randomized Controlled Trial to Assess the Efficacy of Tranexamic Acid for Hemostasis

医院

The Second Affiliated Hospital Zhejiang University School of Medicine

状态

招募中

登记库

NCT06023212

研究 A Phase I/II Multicenter, Open Label, Single-arm Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of WSD0922-FU in the Treatment of Advanced Non-small Cell Lung Cancer

医院

Anhui Provincial Hospital

状态

招募中

登记库

NCT06631989

研究 Targeting Delta-like Ligand 3 (DLL3) With 68Ga-PFD3 PET/CT for the Diagnosis and Assessment of Small Cell Lung Cancer (SCLC)

主要研究者

Tingting Yuan · Attending physician

医院

Peking University First Hospital

状态

招募中

登记库

NCT07508852

研究 Effectiveness of Acupuncture Combined With PD-1/PD-L1 Inhibitors for Advanced Lung Cancer：A Randomized Controlled Clinical Study

主要研究者

Liu Zhishun · professer，Chief Physician

医院

The First Affiliated Hospital of Anhui Medical University

状态

招募中

登记库

NCT06926140

研究 TCR-T Cells Targeting Cancer Cells for Immunotherapy of Lung Cancer and Other Solid Tumors: Phase I Clinical Trial

医院

The Second Affiliated Hospital of Guangzhou Medical University

状态

招募中

登记库

NCT03778814

研究 Observational Study on the Efficacy and Safety of Huaier Granules Compared With Platinum Containing Dual Drug Combination Chemotherapy in Adjuvant Therapy for Resectable Stage II-IIIA Non-small Cell Lung Cancer After Radical Surgery

主要研究者

Hongxu Liu · professor

医院

Liaoning Cancer Hospital

状态

招募中

登记库

NCT06109454

研究 Prospective, Single-arm Phase II Clinical Study of Single-drug Chemotherapy Plus Immunotherapy in Metastatic Non-small Cell Lung Cancer Elderly Patients

主要研究者

HAN GUANG · Chief physician

医院

Hubei Cancer Hospital

状态

招募中

登记库

NCT06032052

研究 ROSETTA Lung-201: A Randomized, Multicenter, Open-label Phase 3 Study of Pumitamig Monotherapy Compared to Durvalumab in Participants With Unresectable Stage III NSCLC Without Progression After Platinum-based Concurrent Chemoradiation Therapy.

医院

Peking University Cancer Hospital

状态

招募中

登记库

NCT07361497

研究 A Single Arm, Open Label, Dose-escalating, Prospective Phase I Clinical Trial Evaluating the Safety, Tolerability and Efficacy of TMT101 Injection Alone in Patients With Advanced Pancreatic Cancer or Non-small Cell Lung Cancer(NSCLC) After Standard Treatment Failure

主要研究者

Wu Wenming · Director, Chief Physician of Basic Surgery, Principal Investigator, Clinical Professor

医院

Peking Union Medical College Hospital

状态

招募中

登记库

NCT06861543

研究 A Prospective Cohort Study of Zorifertinib as a First-line Treatment in Patients With Epidermal Growth Factor Receptor-mutant Advanced Non-small Cell Lung Cancer With Central Nervous System (CNS) Metastases

医院

The First Affiliated Hospital of Anhui Medical University

状态

招募中

登记库

NCT07143045

研究 Low-dose Radiation Therapy and Stereotactic Body Radiation Therapy Combined With PD-1 Inhibitor Sintilimab and Chemotherapy Versus PD-1 Inhibitor Combined With Chemotherapy as First-line Treatment for Patients With Locally Advanced or Metastatic Squamous Cell Lung Cancer: A Randomized, Phase II Multicenter Clinical Trial

主要研究者

You Lu · Chair of Division of Thoracic Tumor Multimodality Treatment

医院

The Second Affiliated Hospital of Chongqing Medical University

状态

招募中

登记库

NCT06121505

研究 Delta-like Protein 3 (DLL3)- Targeted PET Imaging in Small Cell Lung Cancer

医院

First Affiliated Hospital of Guangzhou Medical University

状态

招募中

登记库

NCT07677787

研究 Randomized, Double-Blind, Multicenter Phase III Study of RC148 in Combination With Platinum-Based Chemotherapy Versus Tislelizumab in Combination With Platinum-Based Chemotherapy as First-Line Treatment for Advanced Squamous Non-Small Cell Lung Cancer

医院

The First Affiliated Hospital of Anhui Medical University

状态

招募中

登记库

NCT07416474

研究 A Phase III, Randomised, Double-blind, Placebo-controlled, Multi-centre Study of Almonertinib as Maintenance Therapy in Patients With Locally Advanced, Unresectable EGFR Mutation-positive Non-Small Cell Lung Cancer (Stage III) Who Have Not Progressed Following Definitive, Platinum-based Chemoradiation Therapy

医院

Shandong Cancer Hospital

状态

招募中

登记库

NCT04951635

研究 The Therapeutic Effect of Irinotecan Liposomes Combined With Cisplatin/Carboplatin for Platinum Sensitive Recurrent Small Cell Lung Cancer

状态

招募中

登记库

NCT06467786

研究 A Phase II Clinical Study to Evaluate the Efficacy and Safety of SKB571 Combination Therapy in Participants With Non-Small Cell Lung Cancer (NSCLC)

医院

Peking University Cancer Hospital

状态

招募中

登记库

NCT07622186

研究 Efficacy and Safety of PD-L1 Inhibitor Rechallenge After Immune Checkpoint Inhibitor-Related Pneumonitis in Patients With Lung Cancer: A Multicenter Real-World Study

医院

First Affiliated Hospital of Guangzhou Medical University

状态

招募中

登记库

NCT07775820

研究 Tubeless Anesthesia in Preventing Contralateral Lung Complications in Patients Undergoing Single-Port Thoracoscopic Surgery for Early-Stage Lung Cancer: A Single-Center, Prospective, Open-Label, Randomized Controlled Trial

医院

Fujian Medical University Union Hospital

状态

招募中

登记库

NCT07024433

研究 Effectiveness of Perioperative Percutaneous Acupoint Acupuncture on Postoperative Sleep Disturbances in Patients Undergoing Video-Assisted Thoracoscopic Lung Cancer Resection: A Prospective, Randomized, Single-Blind, Superiority Controlled Trial

主要研究者

LIna Huang · Chief Physician, Department of Anesthesiology, Shanghai First People's Hospital

医院

Shanghai General Hospital

状态

招募中

登记库

NCT07662733

研究 Electroacupuncture Combined With 5-HT3 Receptor Inhibitor for the Prevention of Postoperative Nausea and Vomiting in High-risk Patients Undergoing Thoracoscopic Surgery for Lung Cancer

主要研究者

Cai Xiaoyue · Associate Chief Physician

医院

Shanghai Chest Hospital

状态

招募中

登记库

NCT07515027

研究 Molecular Landscape of Primary and Acquired Resistance to Immune Checkpoint Inhibitors in Patients With Chinese Advanced Non-small Cell Lung Cancer

主要研究者

Xiaomin Niu · Principal Investigator

医院

Shanghai Chest Hospital

状态

招募中

登记库

NCT04977791

研究 Randomized Controlled Study on Improving Patient-reported Outcomes After Lung Cancer Surgery With Mobile Internet Platform

主要研究者

Xinghua Cheng · Director, Head of Oncology Surgery, Clinical Professor

医院

Shanghai Chest Hospital

状态

招募中

登记库

NCT06483295

研究 The Efficacy and Safety of the Combination of Sintilimab With Platinum-doublet Chemotherapy and Adaptive Radiotherapy Strategy in the Treatment of Stage III Non-small Cell Lung Cancer Patients

主要研究者

Xuewen Liu · Professor

医院

Hunan Cancer Hospital

状态

招募中

登记库

NCT07138755

研究 A Phase I Clinical Study to Explore the Safety and Efficacy of Hypervision Proton Surgery (HyPROS) for Early-stage Non-small Cell Lung Cancer

主要研究者

Shuanghu Yuan · Professor

医院

Anhui Provincial Hospital

状态

招募中

登记库

NCT07195084

研究 A Multicenter, Randomized, Double-blind, Phase III Clinical Study of Comparing the Efficacy and Safety of AK112 (PD-1/VEGF Bispecific Antibody) Versus Placebo as Consolidation Treatment for Patients With Limited Stage Small-Cell Lung Cancer Who Have Not Progressed Following Concurrent Chemoradiation Therapy

医院

Peking University Cancer Hospital

状态

招募中

登记库

NCT07010263

研究 Prospective Cohort Study on Risk Factors and Machine Learning-Based Prediction of Postoperative Venous Thromboembolism in Patients Undergoing Lung Cancer Surgery

医院

The First Hospital of Jilin University

状态

招募中

登记库

NCT07439991

研究 An Open Label, First-in-human Study of BAY 2927088 in Participants With Advanced Non-small Cell Lung Cancer (NSCLC) Harboring an EGFR and/or HER2 Mutation

医院

Peking University Cancer Hospital

状态

招募中

登记库

NCT05099172

研究 Exploratory Clinical Study of Adebrelimab Combined With Chemotherapy and Concurrent Radiotherapy Versus Sequential Radiotherapy as First-Line Treatment for Extensive-Stage Small Cell Lung Cancer（ES-SCLC）.

主要研究者

Rong Yu, MD · Investigator Official Title

医院

Peking University Cancer Hospital

状态

招募中

登记库

NCT06768307

研究 A Phase 3 Randomized Open-Label Study of Adjuvant Pembrolizumab With or Without MK-2870 in Participants With Resectable Stage II to IIIB (N2) NSCLC Not Achieving pCR After Receiving Neoadjuvant Pembrolizumab With Platinum-based Doublet Chemotherapy Followed by Surgery

医院

Peking University Cancer Hospital

状态

招募中

登记库

NCT06312137

研究 Clinical Study of CEA Targeting Chimeric Antigen Receptor T Lymphocytes (CAR-T) for CEA Positive Advanced Lung Cancer

状态

招募中

登记库

NCT06992583

研究 Surgery or Radiotherapy After PD-L1 Inhibitor (TQB-2450) and Chemotherapy Induction Therapy in Patients With Limited-stage Small-cell Lung Cancer

主要研究者

Peng Zhang · Director of science and education department

医院

Shanghai Pulmonary Hospital

状态

招募中

登记库

NCT04539977

研究 Exploring the Neo-Adjuvant Therapy Effects on Lung Cancer Through Monitoring and Assessment of Tumor Environment (NAT-LungMate)

主要研究者

Peng Zhang · Professor

医院

Shanghai Pulmonary Hospital

状态

招募中

登记库

NCT05857800

研究 Multicenter, Retrospective, Observational Study of Icotinib for Post-Surgical Adjuvant Therapy in Stage IA2 High-Risk to IB Non-Small-Cell Lung Cancer With Positive EGFR-Sensitive Mutations

医院

Peking University Cancer Hospital

状态

招募中

登记库

NCT07806604

研究 The Shengjing Lung Cancer Cohort (SJ-LCC) Study

主要研究者

Huanhuan Chen · Shengjing Hospital of China Medical University

医院

Shengjing Hospital

状态

招募中

登记库

NCT07779005

研究 A Phase II Study Evaluating Neoadjuvant Chemotherapy, Concurrent Chemoradiotherapy Combined With Dual Immune Checkpoint Blockade (PD-1/CTLA-4) in Patients With Locally Advanced Non-Small Cell Lung Cancer

主要研究者

Hui Liu · Professor

医院

Sun Yat-sen University Cancer Center

状态

招募中

登记库

NCT07103395

研究 LcProt: Proteomics Longitudinal Cohort Study on Lung CancerProspective Longitudinal Cohort Study of Lung Cancer Based on Peripheral Blood and Tissue Proteomics

主要研究者

Jianxing He · Professor

医院

First Affiliated Hospital of Guangzhou Medical University

状态

招募中

登记库

NCT06778512

研究 An Apen-label, Multicenter Phase II Study to Evaluate the Efficacy and Safety of BEBT-109 in Patients With EGFR Exon 20 Insertion Mutations in Locally Advanced or Metastatic Non-Small Cell Lung Cancer

医院

Guangdong Provincial People's Hospital

状态

招募中

登记库

NCT06706713

研究 Short-term Effects of Preoperative Exercise in Moderate-to-high Perioperative Risk Lung Cancer Patients(PRE-EXELUCA): a Prospective Randomized Controlled Clinical Trial

医院

Guangdong Provincial People's Hospital

状态

招募中

登记库

NCT06215326

研究 Beamion 44: A Randomized, Open-label, Multi-center Phase IIa Platform Trial to Evaluate the Safety and Tolerability of Zongertinib Plus Platinum-based Doublet Chemotherapy With or Without Pembrolizumab (and Potential Other Combinations) in Treatment-naïve Patients With Locally Advanced/Metastatic Non-squamous NSCLC With Activating HER2 Mutations

医院

Guangdong Provincial People's Hospital

状态

招募中

登记库

NCT07486817

研究 A Prospective, Multicenter, Randomized Controlled, Phase II Study of Probiotics Combined With Concurrent Hyperfractionated ChemoRadiotherapy and Adebrelimab Immunomaintenance in the Treatment of Limited-stage Small Cell Lung Cancer (LS-SCLC)

主要研究者

Xingwen Fan · associate professor

医院

Fudan University Shanghai Cancer Center

状态

招募中

登记库

NCT06943235

研究 Mechanisms of Enhanced Efficacy of Ivonescimab in Neoadjuvant Therapy for Non-Small Cell Lung Cancer

主要研究者

Yang Fan, MD · Vice President

医院

Peking University People's Hospital

状态

招募中

登记库

NCT07359040

研究 A Phase II/III Clinical Study on the Efficacy and Safety of TQB2450 Injection Combined With Chemotherapy or Anlotinib Hydrochloride Capsule in the Perioperative Treatment of Resectable Stage II/III Non Small Cell Lung Cancer.

医院

Cancer Hospital of Chinese Academy of Medical Sciences

状态

招募中

登记库

NCT05913089

研究 A Phase 3, Multicenter, Randomized, Open-label Study of Ifinatamab Deruxtecan (I-DXd), a B7-H3 Antibody Drug Conjugate (ADC), Versus Treatment of Physician's Choice (TPC) in Subjects With Relapsed Small Cell Lung Cancer (SCLC) (IDeate-Lung02)

医院

China-Japan Friendship Hospital

状态

招募中

登记库

NCT06203210

研究 Development and Application of a Thrombosis Risk Prediction Model in Lung Cancer Patients Treated With Immune Checkpoint Inhibitors

医院

First Affiliated Hospital of Zhengzhou University

状态

招募中

登记库

NCT06950697

研究 Exploration of and Model Establishment of the Regression Pattern of Primary Lesions in Lung Cancer After Definitive Radiotherapy

主要研究者

Guangying Zhu · Clinical Professor, Chief Physician

医院

China-Japan Friendship Hospital

状态

招募中

登记库

NCT06692972

研究 A Phase 1 First-in-Human Study Evaluating Safety, Pharmacokinetics and Efficacy of ABBV 324 in Adults With Hepatocellular Cancer or Squamous Cell Non-Small Cell Lung Cancer

医院

Nanfang Hospital

状态

招募中

登记库

NCT06858813

研究 Cohort Studies of Associations of Psychological Stress With Therapy Efficacy and Prognosis of Lung Cancer, Including Non-small-cell Lung Cancer and Small-cell Lung Cancer With Early and Advanced Staging (STRESS-LUNG)

主要研究者

Fang Wu · Professor

医院

Xiangya Hospital of Central South University

状态

招募中

登记库

NCT05477979

研究 Study of Propranolol Hydrochloride in Combination With Sintilimab and Platinum-based Chemotherapy for Treatment of Advanced Non-small Cell Lung Cancer (BRIO)

主要研究者

Fang Wu · Chief Physician, Associate Professor

医院

Second Xiangya Hospital of Central South University

状态

招募中

登记库

NCT05979818

研究 The Associations of Sleep Disturbance With Therapy Efficacy and Prognosis of Lung Cancer, Including Non-small-cell Lung Cancer and Small-cell Lung Cancer With Early and Advanced Staging

主要研究者

Fang Wu · Professor

医院

Xiangya Hospital of Central South University

状态

招募中

登记库

NCT06975384

研究 Comprehensive Multi-Omics Analysis of Early-Stage Lung Cancer Exhibiting Distinct Phenotypes

主要研究者

Chen Chen · Associate Professor

医院

Second Xiangya Hospital of Central South University

状态

招募中

登记库

NCT06699979

研究 A Prospective, Single-Arm, Multicenter, Phase II Clinical Study of Chidamide Combined With Ivonescimab in the Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC) With Acquired Resistance to Immunotherapy and High Yes-associated Protein (YAP) Expression

医院

Guangdong Provincial People's Hospital

状态

招募中

登记库

NCT07412262

研究 A Phase 3, Multicenter, Randomized, Open-label Trial of Trastuzumab Deruxtecan in Combination With Pembrolizumab Versus Platinum-based Chemotherapy in Combination With Pembrolizumab, as First-line Therapy in Participants With Locally Advanced Unresectable or Metastatic HER2 Overexpressing and PD-L1 TPS <50% Non-squamous Non-small Cell Lung Cancer (DESTINY-Lung06)

医院

Peking University Cancer Hospital

状态

招募中

登记库

NCT06899126

研究 Predicting Immunotherapy Response and Survival of Lung Cancer Patients Using Artificial Intelligence and Radiomics (Radiology-AI-Lung)

医院

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

状态

招募中

登记库

NCT07059923

研究 Assessment the Association of Imaging and Tumor Microenvironment in Lung Cancer With Radiogenomics

医院

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

状态

招募中

登记库

NCT06500312

研究 A Phase II Clinical Study to Evaluate the Efficacy and Safety of SI-B003 Monotherapy and BL-B01D1+SI-B003 Combination Therapy in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer, Nasopharyngeal Carcinoma and Other Solid Tumors

医院

Chongqing University Cancer Hospital

状态

招募中

登记库

NCT05956587

研究 The Application Value of 68Ga-grazytracer PET in Immunotherapy for Stage III Non-small-cell Lung Cancer: a Prospective, Observationa Trial

医院

Ruijin Hospital

状态

招募中

登记库

NCT06623487

研究 A Phase 3 Multicenter Open-label Study of Taletrectinib Versus a Standard of Care ROS1-Tyrosine Kinase Inhibitor (Crizotinib) in TKI-Naïve Patients With ROS1-Positive Locally Advanced or Metastatic Non-Small Cell Lung Cancer (TRUST-III)

医院

The First Affiliated Hospital of Anhui Medical University

状态

招募中

登记库

NCT06564324

研究 Impact of Intraoperative Blood Pressure Management and Dexamethasone on Patient's Outcomes After Lung Cancer Surgery: A 2 × 2 Factorial Randomized Controlled Trial

主要研究者

Dong-Xin Wang · Chairman, Department of Anaesthesiology and Critical Care Medicine

医院

Peking University First Hospital

状态

招募中

登记库

NCT04209218

研究 Penpulimab-based Combination Neoadjuvant/Adjuvant Therapy for Patients With Resectable Locally Advanced Non-small Cell Lung Cancer: a Phase II Clinical Study (ALTER-L043)

医院

The First Affiliated Hospital of Nanchang University

状态

尚未招募

登记库

NCT04846634

研究 A Prospective, Multicenter Clinical Study of Hetrombopag in the Prevention of Thrombocytopenia Caused by Lung Cancer Therapy

主要研究者

Ren Shengxiang · professor

医院

Jiangsu Cancer Hospital

状态

尚未招募

登记库

NCT07101627

研究 INFORM: A Prospective Interventional Study on Early Screening for Lung Cancer Using Liquid Biopsy

主要研究者

Jianxing He · Professor

医院

First Affiliated Hospital of Guangzhou Medical University

状态

尚未招募

登记库

NCT06422637

研究 Selective Mediastinal Lymph Node Sampling Versus Systematic medIastinal Lymph Node Dissection After Neoadjuvant Chemotherapy Combined With Immunotherapy for the Treatment of Clinical Stage IIA-IIIB (N2) Non-small Cell Lung Cancer

主要研究者

Wen-zhao ZHONG · Head of Thoracic Surgery

医院

Guangdong Provincial People's Hospital

状态

尚未招募

登记库

NCT07617389

研究 Iparomlimab and Tuvonralimab (QL1706) Combined Chemotherapy and Quad Shot Radiotherapy in First-line Treatment of Driver Gene-negative Advanced Non-small Cell Lung Cancer: a Randomized, Controlled, Phase 2, Open-label Trial.

医院

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

状态

尚未招募

登记库

NCT07271602

研究 An Open, Multi-center Phase I Clinical Trial to Evaluate the Safety, Tolerability and Preliminary Efficacy of BL0020 Injection in Combination With Toripalimab Injection in Patients With Recurrent Extensive-Stage Small Cell Lung Cancer

医院

Third Affiliated Hospital of Harbin Medical University

状态

尚未招募

登记库

NCT07550842

研究 A Single-arm, Multicenter, Prospective Clinical Study of Adebrelimab Combined With Apatinib Neoadjuvant Therapy for Resectable Non-small Cell Lung Cancer

医院

First Affiliated Hospital of Xiamen University

状态

尚未招募

登记库

NCT07031154

研究 Exploratory Clinical Study on Microwave Ablation With or Without Furmonertinib for Early-Stage Non-Small Cell Lung Cancer

主要研究者

Jiayuan Sun · Chief Physician

医院

Shanghai Chest Hospital

状态

尚未招募

登记库

NCT06969781

研究 Efficacy and Safety of Septum-guided Segmentectomy for 2-3 cm Clinical Stage IA3 Peripheral Non-Small Cell Lung Cancer: A Single-Center, Prospective, Single-Arm Clinical Trial

主要研究者

Junfeng Geng · Professor

医院

Shanghai Chest Hospital

状态

尚未招募

登记库

NCT07780591

研究 An Open-label, Single-center, Phase II Study of Cadonilimab Monotherapy as Neoadjuvant Therapy for Resectable II-IIIA Squamous Cell Lung Cancer

医院

The First Hospital of Jilin University

状态

尚未招募

登记库

NCT05784974

研究 Postoperative Adjuvant Treatment of ALK-positive Non-small Cell Lung Cancer with Ensartinib Guided by MRD: a Single-arm, Multicenter Study

主要研究者

Wu Nan · Professor

医院

Peking University Cancer Hospital

状态

尚未招募

登记库

NCT06780839

研究 Efficacy of PD-1 Inhibitor Combination Therapy in Non-small Cell Lung Cancer Patients Who Have Not Achieved Major Pathologic Response After Neoadjuvant Immunotherapy: a Multicenter, Phase II Clinical Trial

主要研究者

Chang Chen · Deputy Director of MD. PhD. Program in Thoracic Surgery, Secretary of the party committee of Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China

医院

Shanghai Pulmonary Hospital

状态

尚未招募

登记库

NCT06620822

研究 A Multicenter Randomized Controlled Trial of an Intelligent Pulmonary Function Exercise Device Versus Usual Care for In-Hospital and Home-Based Pulmonary Rehabilitation After Lung Cancer Surgery

主要研究者

Jianxing He · Principal Investigator

医院

First Affiliated Hospital of Guangzhou Medical University

状态

尚未招募

登记库

NCT07631520

研究 A Randomized Controlled Trial Evaluating the Effectiveness of a Novel Risk-Stratified Screening Strategy for Lung Cancer

主要研究者

Jianxing He · Principal Investigator

医院

First Affiliated Hospital of Guangzhou Medical University

状态

尚未招募

登记库

NCT07078032

研究 A Clinical Study Evaluating the Safety and Efficacy of Golidocitinib in Patients With Refractory Immune-related Hematologic Toxicities of Advanced Lung Cancer

主要研究者

Jianxing He · Director, Head of Thoracic Surgery, Principal Investigator, Clinical Professor

医院

First Affiliated Hospital of Guangzhou Medical University

状态

尚未招募

登记库

NCT07303881

研究 Predictive Value of CEA and ctDNA for Postoperative Recurrence in Patients With High CEA Sensitivity Lung Cancer

医院

Guangdong Provincial People's Hospital

状态

尚未招募

登记库

NCT07170046

研究 Development of a Chest CT-Based Artificial Intelligence Model Across the Lung Cancer Care Continuum and a Prospective Randomized Crossover Reader Study of Its Clinical Decision-Support Performance

医院

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

状态

尚未招募

登记库

NCT07829640

研究 A Phase II/III Clinical Study Comparing BL-B01D1 in Combination With PD-1/VEGF Bispecific Antibody Versus Chemotherapy in Combination With PD-1/VEGF Bispecific Antibody in First-line Patients With Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer(PANKU-Lung05)

医院

Sun Yat-sen University Cancer Center

状态

尚未招募

登记库

NCT07739199

研究 The Effects of Acupuncture for Lung Cancer-Related Fatigue, a Clinical Trial

主要研究者

Yuanjie Sun · Doctor

医院

Guang'anmen Hospital of China Academy of Chinese Medical Sciences

状态

尚未招募

登记库

NCT07079072

研究 Neoadjuvant Sintilimab Plus Anlotinib Therapy in IB-IIIB Resectable Non-small Cell Lung Cancer (PRIORITY): a Prospective Single Center, Open Label, Phase II Study

医院

Ningbo No.2 Hospital

状态

尚未招募

登记库

NCT06221462

研究 A Randomized, Double-blind, Phase III Trial to Compare the Efficacy and Safety of AK104 Combined With Chemotherapy to Tislelizumab Combined With Chemotherapy as First-line Treatment in PD-L1 TPS < 1% Non-small Cell Lung Cancer (NSCLC)

医院

First Affiliated Hospital of Guangzhou Medical University

状态

尚未招募

登记库

NCT05990127

研究 Randomized Clinical Trials Comparing Immunotherapy Plus Cryoablation (I-CA) Versus Cryoablation Alone for Stage I, Selected Stage IIa, Non-Small Cell Lung Cancer

主要研究者

Jiayuan Sun · Director, Department of Respiratory Endoscopy

医院

Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology

状态

尚未招募

登记库

NCT06580665

研究 Organoid-Based Drug Sensitivity Model Guided Personalized Precision Treatment for Extensive-Stage Small Cell Lung Cancer: A Prospective, Multicenter, Randomized Controlled Trial

医院

Peking Union Medical College Hospital

状态

尚未招募

登记库

NCT07106528

研究 A Randomized Phase 3 Multicenter Open-Label Study to Compare the Efficacy of YK-029A as First-Line Treatment Versus Platinum-Based Chemotherapy in Patients With Non-Small Cell Lung Cancer With EGFR Exon 20 Insertion Mutations

医院

First Affiliated Hospital of Guangzhou Medical University

状态

尚未招募

登记库

NCT05767892

研究 Adebrelimab and Concurrent Radiochemotherapy as First-line Treatment for Extensive-stage Small-cell Lung Cancer

医院

Henan Cancer Hospital

状态

尚未招募

登记库

NCT06236997

研究 An Investigator-initiated Trial Evaluating the Efficacy and Safety of Anti-Trop2 Universal CAR-NK(U-CAR-NK) Cells Therapy Combined With Chemotherapy for Relapsed/Refractory Non-Small Cell Lung Cancer (NSCLC)

主要研究者

Qiming Wang · Professor

医院

Henan Cancer Hospital

状态

尚未招募

登记库

NCT06454890

研究 Adebrelimab Combined With Oral Etoposide for Elderly Patients and Patients With Poor Performance Status in Small Cell Lung Cancer: An Exploratory Clinical Study

主要研究者

Liu Fang · Director

医院

Third Affiliated Hospital of Harbin Medical University

状态

尚未招募

登记库

NCT07398560

研究 Stereotactic Body Radiotherapy With Sequential Iparomlimab and Tuvonralimab (QL1706) + Chemotherapy as Neoadjuvant Therapy in Patients With Resectable Non-small-cell Lung Cancer in China (LUNG-Nanjing01): a Single-arm, Single-centre, Phase 2 Trial

主要研究者

Zhang Zhi · Associate Professor

医院

Jiangsu Cancer Hospital

状态

尚未招募

登记库

NCT07286942

研究 Efficacy and Safety of Induction Chemoimmunotherapy Followed by Carbon Ion Radiotherapy and Consolidation Immunotherapy in Unresectable Locally Advanced Non-small Cell Lung Cancer

主要研究者

Ji Yongling · PI

医院

Zhejiang Cancer Hospital

状态

尚未招募

登记库

NCT07035860

研究 A Prospective, Multicenter, Randomized Controlled Clinical Trial Comparing Bronchoscopic Thermal Vapor Ablation and Percutaneous Microwave Ablation in Patients With COPD and Early-Stage Lung Cancer: Efficacy and Safety Evaluation

医院

Henan Provincial People's Hospital

状态

尚未招募

登记库

NCT06929390

研究 Effects of Different Preoperative Oral Rehydration Protocols on Safety, Comfort, and Postoperative Outcomes in Elderly Patients Undergoing Thoracoscopic Radical Lung Cancer Surgery: A Randomized Controlled Trial

医院

Fujian Medical University Union Hospital

状态

尚未招募

登记库

NCT07042503

研究 The Impact of SGLT2i on the Outcome of Advanced Lung Cancer in Patients With Diabetes

主要研究者

Liang Zhao · Dr

医院

Shanghai Chest Hospital

状态

尚未招募

登记库

NCT07272057

研究 Phase I Study of Anti-EGFR/c-Met Bispecific Antibody MCLA-129 Combined With Befotertinib in Patients of Advanced Non-small Cell Lung Cancer With EGFR Sensitive Mutation To Evaluate The Safety, Pharmacokinetic Characteristics and Antitumor Activity

医院

First Affiliated Hospital of Guangzhou Medical University

状态

尚未招募

登记库

NCT06015568

研究 A Single-Arm Phase II Study of Intrathecal Thiotepa Via Ommaya Reservoir for Leptomeningeal Metastases in Non-Small Cell Lung Cancer Resistant to EGFR-TKI

医院

Tianjin Medical University Cancer Institute & Hospital

状态

尚未招募

登记库

NCT07778940

研究 A Prospective, Multicenter Exploratory Clinical Study on Consolidation Therapy With Tislelizumab Combined With Nintedanib for Limited-stage Small Cell Lung Cancer

医院

The Affiliated Hospital of Qingdao University

状态

尚未招募

登记库

NCT07485920

研究 A Multicenter Exploratory Clinical Study of Iruplaltinib Combined With Pemetrexed as Neoadjuvant Therapy for Resectable ALK-Positive Non-Squamous Non-Small Cell Lung Cancer

医院

The First Affiliated Hospital of Fujian Medical University

状态

尚未招募

登记库

NCT07771764

研究 Comparing the Efficiency Between Surgery and Radiotherapy After SHR-1316 (Adebrelimab) and Platinum-containing Doublet Induction Therapy for Limited-stage Small Cell Lung Cancer: a Randomized, Controlled, Open-label, Single-center Phase III Clinical Trial

主要研究者

Peng Zhang · associate professor of medicine

医院

Shanghai Pulmonary Hospital

状态

尚未招募

登记库

NCT05496166

研究 Furmonertinib Combined With Local Therapy in Inoperable or Surgery-Refusing Early-Stage Non-Small Cell Lung Cancer:A Single-arm, Phase II Study

主要研究者

Xuefei Hu · Chief Physician

医院

Shanghai Pulmonary Hospital

状态

尚未招募

登记库

NCT07517640

研究 A Phase II Clinical Study of Adebelizumab Combined With Other Anti-tumor Treatments as a Perioperative Treatment for Resectable Non-small Cell Lung Cancer

医院

Shanghai Pulmonary Hospital

状态

尚未招募

登记库

NCT07704645

研究 An Observational Study on the Impact of the 23-valent Pneumonia Vaccine on the Incidence of Pulmonary Infection and Survival in Lung Cancer Patients

主要研究者

Yalei Zhang · The First Affiliated Hospital of Guangzhou Medical University

医院

First Affiliated Hospital of Guangzhou Medical University

状态

尚未招募

登记库

NCT07142057

研究 Explore the Mechanisms Underlying Disease Resistance and Potential Primary Resistance Mechanism of Induction Therapy Lorlatinib in Resectable Non-small Cell Lung Cancer (NSCLC) Harboring ALK Positive Mutation Revealed by Single-cell RNA Sequencing and Spatial Transcriptomics

主要研究者

Jianxing He · Chief physician

医院

First Affiliated Hospital of Guangzhou Medical University

状态

尚未招募

登记库

NCT06893354

研究 Phase II, Open-label, Single-arm, Prospective, Multi-center Study to Evaluate the Efficacy and Safety of Lorlatinib as Neoadjuvant Treatment in Surgically Resectable Stage IB-IIIB ALK-rearranged Non-Small Cell Lung Cancer (NEOLORA)

主要研究者

Yang Fan, MD · Professor of Thoracic Surgery

医院

Peking University People's Hospital

状态

尚未招募

登记库

NCT06682884

研究 The Diagnostic Value of Bronchoscopic Needle-based Confocal Laser Endomicroscopy (nCLE) As a Real-time Detection Tool for Diagnosing Peripheral Lung Cancer: a Multi-centre Randomised Controlled Trial

主要研究者

Gang Hou · Professor

医院

China-Japan Friendship Hospital

状态

尚未招募

登记库

NCT06739421

研究 A Multi-cohort, Open-label Phase II Study to Evaluate the Efficacy and Safety of the Anti-EGFR/c-Met Bispecific Antibody MCLA-129 in Patients with Advanced Non-Small Cell Lung Cancer with Actionable Gene Alterations and MET Amplification.

医院

The First Affiliated Hospital of Anhui Medical University

状态

尚未招募

登记库

NCT06885840